diff --git a/erpnext/accounts/doctype/purchase_invoice/purchase_invoice.py b/erpnext/accounts/doctype/purchase_invoice/purchase_invoice.py
index 48b5cb9..f4fd1bf 100644
--- a/erpnext/accounts/doctype/purchase_invoice/purchase_invoice.py
+++ b/erpnext/accounts/doctype/purchase_invoice/purchase_invoice.py
@@ -114,6 +114,9 @@
 		self.set_status()
 		self.validate_purchase_receipt_if_update_stock()
 		validate_inter_company_party(self.doctype, self.supplier, self.company, self.inter_company_invoice_reference)
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
+		self.reset_default_field_value("rejected_warehouse", "items", "rejected_warehouse")
+		self.reset_default_field_value("set_from_warehouse", "items", "from_warehouse")
 
 	def validate_release_date(self):
 		if self.release_date and getdate(nowdate()) >= getdate(self.release_date):
diff --git a/erpnext/accounts/doctype/sales_invoice/sales_invoice.py b/erpnext/accounts/doctype/sales_invoice/sales_invoice.py
index c4d59f1..64712b5 100644
--- a/erpnext/accounts/doctype/sales_invoice/sales_invoice.py
+++ b/erpnext/accounts/doctype/sales_invoice/sales_invoice.py
@@ -155,6 +155,8 @@
 		if self.redeem_loyalty_points and self.loyalty_program and self.loyalty_points and not self.is_consolidated:
 			validate_loyalty_points(self, self.loyalty_points)
 
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
+
 	def validate_fixed_asset(self):
 		for d in self.get("items"):
 			if d.is_fixed_asset and d.meta.get_field("asset") and d.asset:
diff --git a/erpnext/buying/doctype/purchase_order/purchase_order.py b/erpnext/buying/doctype/purchase_order/purchase_order.py
index 5eab21b..1b5f35e 100644
--- a/erpnext/buying/doctype/purchase_order/purchase_order.py
+++ b/erpnext/buying/doctype/purchase_order/purchase_order.py
@@ -72,6 +72,7 @@
 		self.create_raw_materials_supplied("supplied_items")
 		self.set_received_qty_for_drop_ship_items()
 		validate_inter_company_party(self.doctype, self.supplier, self.company, self.inter_company_order_reference)
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
 
 	def validate_with_previous_doc(self):
 		super(PurchaseOrder, self).validate_with_previous_doc({
diff --git a/erpnext/controllers/tests/test_transaction_base.py b/erpnext/controllers/tests/test_transaction_base.py
new file mode 100644
index 0000000..13aa697
--- /dev/null
+++ b/erpnext/controllers/tests/test_transaction_base.py
@@ -0,0 +1,22 @@
+import unittest
+
+import frappe
+
+
+class TestUtils(unittest.TestCase):
+    def test_reset_default_field_value(self):
+        doc = frappe.get_doc({
+            "doctype": "Purchase Receipt",
+            "set_warehouse": "Warehouse 1",
+        })
+
+        # Same values
+        doc.items = [{"warehouse": "Warehouse 1"}, {"warehouse": "Warehouse 1"}, {"warehouse": "Warehouse 1"}]
+        doc.reset_default_field_value("set_warehouse", "items", "warehouse")
+        self.assertEqual(doc.set_warehouse, "Warehouse 1")
+
+        # Mixed values
+        doc.items = [{"warehouse": "Warehouse 1"}, {"warehouse": "Warehouse 2"}, {"warehouse": "Warehouse 1"}]
+        doc.reset_default_field_value("set_warehouse", "items", "warehouse")
+        self.assertEqual(doc.set_warehouse, None)
+
diff --git a/erpnext/selling/doctype/sales_order/sales_order.py b/erpnext/selling/doctype/sales_order/sales_order.py
index e69e28d..cc95185 100755
--- a/erpnext/selling/doctype/sales_order/sales_order.py
+++ b/erpnext/selling/doctype/sales_order/sales_order.py
@@ -63,6 +63,8 @@
 		if not self.billing_status: self.billing_status = 'Not Billed'
 		if not self.delivery_status: self.delivery_status = 'Not Delivered'
 
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
+
 	def validate_po(self):
 		# validate p.o date v/s delivery date
 		if self.po_date and not self.skip_delivery_note:
diff --git a/erpnext/stock/doctype/delivery_note/delivery_note.py b/erpnext/stock/doctype/delivery_note/delivery_note.py
index 5268460..70d48a4 100644
--- a/erpnext/stock/doctype/delivery_note/delivery_note.py
+++ b/erpnext/stock/doctype/delivery_note/delivery_note.py
@@ -138,6 +138,7 @@
 		self.update_current_stock()
 
 		if not self.installation_status: self.installation_status = 'Not Installed'
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
 
 	def validate_with_previous_doc(self):
 		super(DeliveryNote, self).validate_with_previous_doc({
diff --git a/erpnext/stock/doctype/material_request/material_request.py b/erpnext/stock/doctype/material_request/material_request.py
index d717c50..103e8d6 100644
--- a/erpnext/stock/doctype/material_request/material_request.py
+++ b/erpnext/stock/doctype/material_request/material_request.py
@@ -80,6 +80,9 @@
 		# NOTE: Since Item BOM and FG quantities are combined, using current data, it cannot be validated
 		# Though the creation of Material Request from a Production Plan can be rethought to fix this
 
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
+		self.reset_default_field_value("set_from_warehouse", "items", "from_warehouse")
+
 	def set_title(self):
 		'''Set title as comma separated list of items'''
 		if not self.title:
diff --git a/erpnext/stock/doctype/purchase_receipt/purchase_receipt.py b/erpnext/stock/doctype/purchase_receipt/purchase_receipt.py
index 762f45f..c97b306 100644
--- a/erpnext/stock/doctype/purchase_receipt/purchase_receipt.py
+++ b/erpnext/stock/doctype/purchase_receipt/purchase_receipt.py
@@ -118,6 +118,10 @@
 		if getdate(self.posting_date) > getdate(nowdate()):
 			throw(_("Posting Date cannot be future date"))
 
+		self.reset_default_field_value("set_warehouse", "items", "warehouse")
+		self.reset_default_field_value("rejected_warehouse", "items", "rejected_warehouse")
+		self.reset_default_field_value("set_from_warehouse", "items", "from_warehouse")
+
 
 	def validate_cwip_accounts(self):
 		for item in self.get('items'):
diff --git a/erpnext/stock/doctype/stock_entry/stock_entry.py b/erpnext/stock/doctype/stock_entry/stock_entry.py
index a38dfa5..a00d63e 100644
--- a/erpnext/stock/doctype/stock_entry/stock_entry.py
+++ b/erpnext/stock/doctype/stock_entry/stock_entry.py
@@ -103,6 +103,8 @@
 		self.set_actual_qty()
 		self.calculate_rate_and_amount()
 		self.validate_putaway_capacity()
+		self.reset_default_field_value("from_warehouse", "items", "s_warehouse")
+		self.reset_default_field_value("to_warehouse", "items", "t_warehouse")
 
 	def on_submit(self):
 		self.update_stock_ledger()
diff --git a/erpnext/utilities/transaction_base.py b/erpnext/utilities/transaction_base.py
index 14b3afa..1d8b3a8 100644
--- a/erpnext/utilities/transaction_base.py
+++ b/erpnext/utilities/transaction_base.py
@@ -162,6 +162,28 @@
 
 		return ret
 
+	def reset_default_field_value(self, default_field: str, child_table: str, child_table_field: str):
+		""" Reset "Set default X" fields on forms to avoid confusion.
+
+			example:
+				doc = {
+					"set_from_warehouse": "Warehouse A",
+					"items": [{"from_warehouse": "warehouse B"}, {"from_warehouse": "warehouse A"}],
+				}
+				Since this has dissimilar values in child table, the default field will be erased.
+
+				doc.reset_default_field_value("set_from_warehouse", "items", "from_warehouse")
+			"""
+		child_table_values = set()
+
+		for row in self.get(child_table):
+			child_table_values.add(row.get(child_table_field))
+
+		if len(child_table_values) > 1:
+			self.set(default_field, None)
+		else:
+			self.set(default_field, list(child_table_values)[0])
+
 def delete_events(ref_type, ref_name):
 	events = frappe.db.sql_list(""" SELECT
 			distinct `tabEvent`.name