diff --git a/erpnext/accounts/doctype/bank_transaction/test_bank_transaction.py b/erpnext/accounts/doctype/bank_transaction/test_bank_transaction.py
index 2754633..e9fc5f0 100644
--- a/erpnext/accounts/doctype/bank_transaction/test_bank_transaction.py
+++ b/erpnext/accounts/doctype/bank_transaction/test_bank_transaction.py
@@ -9,11 +9,13 @@
 from erpnext.accounts.doctype.purchase_invoice.test_purchase_invoice import make_purchase_invoice
 from erpnext.accounts.doctype.payment_entry.test_payment_entry import get_payment_entry
 from erpnext.accounts.page.bank_reconciliation.bank_reconciliation import reconcile, get_linked_payments
+from erpnext.accounts.doctype.pos_profile.test_pos_profile import make_pos_profile
 
 test_dependencies = ["Item", "Cost Center"]
 
 class TestBankTransaction(unittest.TestCase):
 	def setUp(self):
+		make_pos_profile()
 		add_transactions()
 		add_payments()
 
@@ -27,6 +29,9 @@
 		frappe.db.sql("""delete from `tabPayment Entry Reference`""")
 		frappe.db.sql("""delete from `tabPayment Entry`""")
 
+		# Delete POS Profile
+		frappe.db.sql("delete from `tabPOS Profile`")
+
 		frappe.flags.test_bank_transactions_created = False
 		frappe.flags.test_payments_created = False
 
diff --git a/erpnext/accounts/doctype/pos_profile/test_pos_profile.py b/erpnext/accounts/doctype/pos_profile/test_pos_profile.py
index edf8659..62dc1fc 100644
--- a/erpnext/accounts/doctype/pos_profile/test_pos_profile.py
+++ b/erpnext/accounts/doctype/pos_profile/test_pos_profile.py
@@ -70,6 +70,7 @@
 		""".format(cond=cond), tuple([company] + args_list), as_dict=1)
 
 def make_pos_profile(**args):
+	frappe.db.sql("delete from `tabPOS Payment Method`")
 	frappe.db.sql("delete from `tabPOS Profile`")
 
 	args = frappe._dict(args)
diff --git a/erpnext/accounts/doctype/sales_invoice/sales_invoice.py b/erpnext/accounts/doctype/sales_invoice/sales_invoice.py
index 0b16763..81f425f 100644
--- a/erpnext/accounts/doctype/sales_invoice/sales_invoice.py
+++ b/erpnext/accounts/doctype/sales_invoice/sales_invoice.py
@@ -405,6 +405,8 @@
 		from erpnext.stock.get_item_details import get_pos_profile_item_details, get_pos_profile
 		if not self.pos_profile:
 			pos_profile = get_pos_profile(self.company) or {}
+			if not pos_profile:
+				frappe.throw(_("No POS Profile found. Please create a New POS Profile first"))
 			self.pos_profile = pos_profile.get('name')
 
 		pos = {}
diff --git a/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py b/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py
index 9660c95..46e954d 100644
--- a/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py
+++ b/erpnext/accounts/doctype/sales_invoice/test_sales_invoice.py
@@ -690,7 +690,8 @@
 		self.assertTrue(gle)
 
 	def test_pos_gl_entry_with_perpetual_inventory(self):
-		make_pos_profile()
+		make_pos_profile(company="_Test Company with perpetual inventory", income_account = "Sales - TCP1", 
+			expense_account = "Cost of Goods Sold - TCP1", warehouse="Stores - TCP1", cost_center = "Main - TCP1", write_off_account="_Test Write Off - TCP1")
 
 		pr = make_purchase_receipt(company= "_Test Company with perpetual inventory", item_code= "_Test FG Item",warehouse= "Stores - TCP1",cost_center= "Main - TCP1")
 
@@ -746,7 +747,8 @@
 		self.assertEqual(pos_return.get('payments')[0].amount, -1000)
 
 	def test_pos_change_amount(self):
-		make_pos_profile()
+		make_pos_profile(company="_Test Company with perpetual inventory", income_account = "Sales - TCP1", 
+			expense_account = "Cost of Goods Sold - TCP1", warehouse="Stores - TCP1", cost_center = "Main - TCP1", write_off_account="_Test Write Off - TCP1")
 
 		pr = make_purchase_receipt(company= "_Test Company with perpetual inventory",
 			item_code= "_Test FG Item",warehouse= "Stores - TCP1", cost_center= "Main - TCP1")
diff --git a/erpnext/healthcare/doctype/fee_validity/test_fee_validity.py b/erpnext/healthcare/doctype/fee_validity/test_fee_validity.py
index cdf692e..7e7fd82 100644
--- a/erpnext/healthcare/doctype/fee_validity/test_fee_validity.py
+++ b/erpnext/healthcare/doctype/fee_validity/test_fee_validity.py
@@ -7,6 +7,7 @@
 import unittest
 from frappe.utils import nowdate, add_days
 from erpnext.healthcare.doctype.patient_appointment.test_patient_appointment import create_healthcare_docs, create_appointment, create_healthcare_service_items
+from erpnext.accounts.doctype.pos_profile.test_pos_profile import make_pos_profile
 
 test_dependencies = ["Company"]
 
@@ -15,6 +16,7 @@
 		frappe.db.sql("""delete from `tabPatient Appointment`""")
 		frappe.db.sql("""delete from `tabFee Validity`""")
 		frappe.db.sql("""delete from `tabPatient`""")
+		make_pos_profile()
 
 	def test_fee_validity(self):
 		item = create_healthcare_service_items()
diff --git a/erpnext/healthcare/doctype/patient_appointment/test_patient_appointment.py b/erpnext/healthcare/doctype/patient_appointment/test_patient_appointment.py
index eeed157..3df7ba1 100644
--- a/erpnext/healthcare/doctype/patient_appointment/test_patient_appointment.py
+++ b/erpnext/healthcare/doctype/patient_appointment/test_patient_appointment.py
@@ -7,12 +7,14 @@
 from erpnext.healthcare.doctype.patient_appointment.patient_appointment import update_status, make_encounter
 from frappe.utils import nowdate, add_days
 from frappe.utils.make_random import get_random
+from erpnext.accounts.doctype.pos_profile.test_pos_profile import make_pos_profile
 
 class TestPatientAppointment(unittest.TestCase):
 	def setUp(self):
 		frappe.db.sql("""delete from `tabPatient Appointment`""")
 		frappe.db.sql("""delete from `tabFee Validity`""")
 		frappe.db.sql("""delete from `tabPatient Encounter`""")
+		make_pos_profile()
 
 	def test_status(self):
 		patient, medical_department, practitioner = create_healthcare_docs()
diff --git a/erpnext/healthcare/doctype/patient_medical_record/test_patient_medical_record.py b/erpnext/healthcare/doctype/patient_medical_record/test_patient_medical_record.py
index aa85a23..419d956 100644
--- a/erpnext/healthcare/doctype/patient_medical_record/test_patient_medical_record.py
+++ b/erpnext/healthcare/doctype/patient_medical_record/test_patient_medical_record.py
@@ -6,11 +6,13 @@
 import frappe
 from frappe.utils import nowdate
 from erpnext.healthcare.doctype.patient_appointment.test_patient_appointment import create_encounter, create_healthcare_docs, create_appointment
+from erpnext.accounts.doctype.pos_profile.test_pos_profile import make_pos_profile
 
 class TestPatientMedicalRecord(unittest.TestCase):
 	def setUp(self):
 		frappe.db.set_value('Healthcare Settings', None, 'enable_free_follow_ups', 0)
 		frappe.db.set_value('Healthcare Settings', None, 'automate_appointment_invoicing', 1)
+		make_pos_profile()
 
 	def test_medical_record(self):
 		patient, medical_department, practitioner = create_healthcare_docs()